估计阅读时长: 10 分钟https://gcmodeller.org/ 流平衡分析(flux balance analysis)是一种可以用来构建和模拟分析基因组级别的代谢网络的数学方法。流平衡分析是系统生物学(system biology)的一个重要的分析手段。不同于以湿实验的代谢通量分析(metabolic flux analysis, MFA),FBA是用数学方法对代谢网络里的代谢流进行拟合分析。 Order by Date Name Attachments Electron micrographs of […]
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其实,你不应该直接跑原始表达矩阵的。因为在原始表达矩阵中,基因的特征数量可能会非常多,做随机森林或者SVM建模就会会非常久。应该先用limma程序包对矩阵筛选一次,例如用log2fc绝对值按照阈值cutoff筛选一次,或者对log2fc绝对值排序后取前1000个特征,得到小一些feature集合的矩阵后再使用这个程序包做机器学习分析。
Thanks for taking the time to create this.
就是随便看看!
c⌒っ゚Д゚)っ救命啊,谢老师,我试了下用这个程序包直接跑转录组矩阵,跑了好久都没有结果
Could you provide some practical examples of how this R package is used? For instance, how does it perform when…